From the Airport of Rome Leonardo da Vinci (Fiumicino) it is possible to take a taxi directly to the flat (45 euro) or take the urban train from the airport to the Termini Railroad Station and hence a bus 360 to the apartment up to Piazza Epiro, then it is walking distance (100 m). The route train+ bus is of about 1 hour. From the airport of Rome Ciampino it is possible to take a taxi (35-40 euro)or a shuttle that reaches the Termini Railroad Station, hence the bus 360to the apartment up to Piazza Epiro, then it is walking distance (100 m). The route train+ bus is of about 45 minutes.
You will feel you have chosen the ideal place to visit Rome: you only need a good pair of shoes since everything is walking distance. In the morning you can drink a cappuccino and cornetto at the bar round the corner in the same building, in the evening you could sit in the open air restaurant Romolo e Remo 150 m from the apartment or eat a pizza at the taverna dei Quaranta in front of the Colosseo.